研究のタイプ: 医学/生物学の研究 (experimental study)

[保存された赤血球の品質に対する13.56MHz無線自動識別システムの影響] med./bio.

Impact of 13.56-MHz radiofrequency identification systems on the quality of stored red blood cells.

掲載誌: Transfusion 2011; 51 (11): 2384-2390

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研究目的(著者による)

To study the biologic effect of 13.56 MHz RFID technology on blood product samples that might be caused by long-term exposure (0-42 days).

詳細情報

RFID application is used for temperature measurement of stored blood products to support the decision of discarding or further using a blood product.
16 red blood cell units were stored at 4±2°C for 42 days. 12 units were used as control samples and 4 units were used as test samples (exposure).

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 13.56 MHz
ばく露時間: continuous for 42 days

ばく露1

主たる特性
周波数 13.56 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 42 days
ばく露装置
ばく露の発生源/構造
  • Siemens Moby SLG D12 RFID reader-writer with a 6 cm x 12 cm antenna
チャンバの詳細 410 cm x 350 cm x 280 cm cold storage room with an ambient temperature of 4±2°C
ばく露装置の詳細 RFID system consisting of a semiactive RFID tag on the blood sample bag and a RFID reader-writer; operating distance 0 - 120 mm; experiments done in the cold storage room
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
電力 1 W - - - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

In both groups glucose and pH levels decreased while lactate, free hemoglobin, and potassium increased within the expected levels. The hemolysis rate showed an increase after the 25th day in both groups (with slightly higher values in the exposed samples) but remained below the maximum acceptable limit value of 0.8%. Significant differences between exposure and control groups were observed in the levels of hemoglobin and hematocrit on day 7, pH on days 14, 21, and 28, and lactate on days 28 and 35, but during the whole study biochemical changes in all samples remained within the normal expected values.
In conclusion, all variables measured remained within the acceptable limits in both groups, without detecting any obvious adverse effects of RFID on red blood cells; therefore, one can conclude that it is feasible to implement RFID-enabled processes.

研究の種別:

研究助成

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