Study type: Medical/biological study (experimental study)

Investigation of a weak magnetic field effect on the in vitro catalytic activity of adenosine deaminase and xanthine oxidase. med./bio.

Published in: Gen Physiol Biophys 2011; 30 (4): 410-414

Aim of study (acc. to author)

To investigate the effects of exposure to extremely low frequency magnetic fields on the enzyme activities of the adenosine deaminase and xanthine oxidase.

Background/further details

The enzyme activity was determined at different time points after exposure, from 0 to 250 minutes.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for up to 250 min

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Exposure duration continuous for up to 250 min
Exposure setup
Exposure source
Setup pair of round Helmholtz coils with a radius of 17.5 cm, placed 17.5 cm apart; samples placed in the center of the coil system
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 5.8 mT - calculated - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • before exposure
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

The enzyme activity of the adenosine deaminase decreased over time in exposed and unexposed samples. However, in magnetic field exposed samples of adenosine deaminase, the curve of the enzyme solution showed a significant steeper decline compared to samples of the control group.
The enzyme activity of the xanthine oxidase was significantly increased in exposed samples compared to unexposed samples. Most of this increase occurred during the first few seconds.
The data indicate that extremely low frequency magnetic fields can affect enzymatic systems.

Study character:

Study funded by

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