Study type: Medical/biological study (experimental study)

Effects of high-frequency electromagnetic fields on human lymphocytes in vitro med./bio.

By: Antonopoulos A, Eisenbrandt H, Obe G
Published in: Mutat Res Genet Toxicol Environ Mutagen 1997; 395 (2-3): 209-214
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Aim of study (acc. to author)

To investigate the effects of high-frequency electromagnetic fields on the cell cycle of human peripheral lymphocytes in the present of phytohemagglutinin in vitro.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 380 MHz
Modulation type: pulsed
Exposure duration: 48 h, 52 h, 56 h, 64 h and 68 h
Exposure 2: 900 MHz
Modulation type: pulsed
Exposure duration: 48 h, 52 h, 56 h, 64 h and 68 h
Exposure 3: 1.8 GHz
Modulation type: pulsed
Exposure duration: 48 h, 52 h, 56 h, 64 h and 68 h

Exposure 1

Main characteristics
Frequency 380 MHz
Type
Charakteristic
  • guided field
Exposure duration 48 h, 52 h, 56 h, 64 h and 68 h
Modulation
Modulation type pulsed
Additional info

Pulse modulated at 17,65 Hz
Exposure setup
Exposure source
Chamber TEM cell/600 mm x 600 mm x 600mm
Setup Culture tubes were held on a round sample holder (140 mm x 140 mm x 160 mm) which was placed in the center of TEM cell. An identical sample holder was used for controls.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 21.8 V/m unspecified calculated - -
SAR 80 mW/kg mean calculated - -
magnetic flux density 0.76 µT unspecified calculated - -
Additional parameter details

Magnetic field density was 0.76 µT

Measurement and calculation details

Field distributation and SARs were determined by MAFIA (Maxwell`s equations by finite integration algorithm).

Exposure 2

Main characteristics
Frequency 900 MHz
Type
Charakteristic
  • guided field
Exposure duration 48 h, 52 h, 56 h, 64 h and 68 h
Modulation
Modulation type pulsed
Repetition frequency 217 Hz
Exposure setup
Exposure source
Chamber TEM cell/ 129.5x259x1300mm
Setup Cultures were held on a rectangular sampel holder (250 mm x 35 mm x 70 mm) which was located in the center of the TEM-cell.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 42.1 V/m unspecified calculated - -
SAR 208 mW/kg mean calculated - -
magnetic flux density 1.2 µT unspecified calculated - -
Additional parameter details

Magnetic field density was 1.2 µT

Exposure 3

Main characteristics
Frequency 1.8 GHz
Type
Charakteristic
  • guided field
Exposure duration 48 h, 52 h, 56 h, 64 h and 68 h
Modulation
Modulation type pulsed
Repetition frequency 217 Hz
Exposure setup
Exposure source
Chamber TEM cell/79 mm x 158 mm x1300 mm ;H10, rectangular sampel holder 250x35x70mm for 6 20ml polystyrole tubes
Setup Culture tubes were held by a sampel holder (250 mm x 35 mm x 70mm) which was placed in the center of the TEM-cell. Control cultures were placed in an electromagnetic protected container.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 127.7 V/m unspecified calculated - -
SAR 1,700 mW/kg mean calculated - -
magnetic flux density 3.1 µT unspecified calculated - -
Additional parameter details

Magnetic field density was 3.1 µT

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

380, 900 and 1800 MHz exposure did not affect the cell cycle in phytohemagglutinin-stimutaled human peripheral lymphocytes.

Study character:

Study funded by

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