Study type: Medical/biological study (experimental study)

The effect of pulsed electromagnetic radiation from mobile phone on the levels of monoamine neurotransmitters in four different areas of rat brain. med./bio.

Published in: Eur Rev Med Pharmacol Sci 2013; 17 (13): 1782-1788

Aim of study (acc. to author)

To examine the effect of an exposure to electromagnetic fields emitted by mobile phones on the concentrations of neurotransmitters in the rat brain.

Background/further details

4 groups of rats were sacrified and examined after: 1.) daily exposure for one month, 2.) daily exposure for two month, 3.) daily exposure for four month and 4.) daily exposure for four month and afterwards 1 month without exposure. Control groups were daily sham exposed in similar containers for the same periods (remark EMF-Portal: no information about number of animals).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 1,800 MHz
Modulation type: pulsed
Exposure duration: 1 h/day for 1, 2 or 4 month

Exposure 1

Main characteristics
Frequency 1,800 MHz
Type
Waveform
Exposure duration 1 h/day for 1, 2 or 4 month
Modulation
Modulation type pulsed
Repetition frequency 217 Hz
Exposure setup
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.843 W/kg - - - -
power density 0.02 mW/cm² - - - -

Reference articles

  • Khadrawy VA et al. (2009): Effect of electromagnetic radiation from mobile phone on the levels of cortical amino acid neurotransmitters in adult and young rats.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In the exposed groups, the level of serotonin was sometimes significantly increased compared to the corresponding control group (in hippocampus in groups 1, 2 and 4; in hypothalamus in groups 3 and 4; in midbrain in group 3).
Additionally, differences occurred regarding the level of dopamine, but sometimes the level in the exposed group was significantly decreased (in hippocampus in group 2 and 4; in hypothalamus in group 2; in midbrain in group 4) and sometimes significantly increased (in hypothalamus in group 3) in comparison to the control group.
Also in the case of norepinephrine, significantly increased (in hippocampus in group 3) and decreased levels (in midbrain in group 2 and 4) were found in comparison to the control group.
The authors conclude that exposure to electromagnetic fields emitted by mobile phones could alter the level of neurotransmitters in the rat brain.

Study character:

Study funded by

Related articles