Study type: Medical/biological study (experimental study)

Variations in amino acid neurotransmitters in some brain areas of adult and young male albino rats due to exposure to mobile phone radiation med./bio.

Published in: Eur Rev Med Pharmacol Sci 2011; 15 (7): 729-742

Aim of study (acc. to author)

To study the effect of one hour daily exposure to electromagnetic fields with a frequency of 900 MHz on the levels of amino acid neurotransmitters in the midbrain, cerebellum and medulla of adult (four month) and young (one month) male rats.

Background/further details

The determination of amino acid levels was carried out after one hour of exposure and following one, two and four months of exposure as well as one month after termination of exposure of four months. The subgroups of the different removed animal groups comprised 5-8 animals.



Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: continuous for 1 h/day for up to 4 months

Exposure 1

Main characteristics
Frequency 900 MHz
Exposure duration continuous for 1 h/day for up to 4 months
Exposure setup
Exposure source
  • not specified
Sham exposure A sham exposure was conducted.
Measurand Value Type Method Mass Remarks
power density 0.02 mW/cm² - - - -
SAR 1.165 W/kg - - - -

Reference articles

  • Khadrawy VA et al. (2009): Effect of electromagnetic radiation from mobile phone on the levels of cortical amino acid neurotransmitters in adult and young rats

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

The data showed a significant increase in both excitatory and inhibitory amino acids in the cerebellum of adult and young rats as well as in the midbrain of adult animals after one hour of electromagnetic field exposure. In the midbrain of adult animals, there were significant increases in the glycine level (after one month) and in the GABA level (after one hour and four months).
Young rats showed significant decreases in the midbrain excitatory amino acids.
In the medulla, the data showed a state of neurochemical inhibition in adult animals after four months, whereas in young animals, the neurochemical inhibitory state was observed after one month of exposure due to significant decreases in glutamate and aspartate levels. This state was converted to an excitation state after 4 months due to the increase in glutamate level.
The authors conclude that the changes in amino acid concentrations may underlie adverse effects of mobile phone use.

Study character:

Study funded by

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