Study type: Medical/biological study (experimental study)

Calcium-ion efflux from brain tissue: power-density versus internal field-intensity dependencies at 50-MHz RF radiation med./bio.

Published in: Bioelectromagnetics 1980; 1 (3): 277-283

Aim of study (acc. to author)

To investigate the effects of 50 MHz radiofrequency irradiation on the calcium-ion efflux from avian brain tissue in vitro.

Background/further details

After decapitation chick forebrain was removed, followed by a labeling period with radioactive calcium solution which was aspirated by the tissue.



Exposure Parameters
Exposure 1: 50 MHz
Modulation type: AM
Exposure duration: continuous for 20 min
  • power density: 3.7 W/m² minimum (0.72 mW/cm², 1.44 mW/cm², 1.67 mW/cm², 2.17 mW/cm², 3.64 mW/cm² and 4.32 mW/cm²)

Exposure 1

Main characteristics
Frequency 50 MHz
  • guided field
Exposure duration continuous for 20 min
Modulation type AM
Modulation frequency 16 Hz
Modulation depth 95 %
Exposure setup
Exposure source
Setup Tissue samples were held in polycarbonate racks which were placed on either side of the transmission line`s center conductor.
Additional info A foamed polystyrene chamber maintained at 37°C housed the transmission line. Control samples were placed on shelves with the chamber adjecent to the transmission line maintained at the same temperature.
Measurand Value Type Method Mass Remarks
power density 3.7 W/m² minimum measured - 0.72 mW/cm², 1.44 mW/cm², 1.67 mW/cm², 2.17 mW/cm², 3.64 mW/cm² and 4.32 mW/cm²

Reference articles

  • Blackman CF et al. (1979): Induction of calcium-ion efflux from brain tissue by radio frequency radiation: Effects of modulation frequency and field strength

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

A statistically significant increase of calcium-ion efflux was observed at power densities of 1.44, 1.67, and 3,64 mW/cm2.

Study character:

Study funded by

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