EMF-Portal | Calcium-ion efflux from brain tissue: power-density versus internal field-intensity dependencies at 50-MHz RF radiation

Calcium-ion efflux from brain tissue: power-density versus internal field-intensity dependencies at 50-MHz RF radiation med./bio.

By: Blackman CF, Benane SG, Joines WT, Hollis MA, House DE

Published in: Bioelectromagnetics 1980; 1 (3): 277-283

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Aim of study (acc. to author)

Background/further details

After decapitation chick forebrain was removed, followed by a labeling period with radioactive calcium solution which was aspirated by the tissue.

Endpoint

Exposure

Exposure	Parameters
Exposure 1: 50 MHz Modulation type: AM Exposure duration: continuous for 20 min	power density: 3.7 W/m² minimum (0.72 mW/cm², 1.44 mW/cm², 1.67 mW/cm², 2.17 mW/cm², 3.64 mW/cm² and 4.32 mW/cm²)

Exposure 1

Main characteristics

Frequency	50 MHz
Charakteristic	guided field
Exposure duration	continuous for 20 min

Modulation

Modulation type	AM
Modulation frequency	16 Hz
Modulation depth	95 %

Exposure setup

Exposure source	Crawford cell
Setup	Tissue samples were held in polycarbonate racks which were placed on either side of the transmission line`s center conductor.
Additional info	A foamed polystyrene chamber maintained at 37°C housed the transmission line. Control samples were placed on shelves with the chamber adjecent to the transmission line maintained at the same temperature.

Parameters

Measurand	Value	Type	Method	Mass	Remarks
power density	3.7 W/m²	minimum	measured	-	0.72 mW/cm², 1.44 mW/cm², 1.67 mW/cm², 2.17 mW/cm², 3.64 mW/cm² and 4.32 mW/cm²

Reference articles

Blackman CF et al. (1979): Induction of calcium-ion efflux from brain tissue by radio frequency radiation: Effects of modulation frequency and field strength

Exposed system:

isolated organ
chicken brain tissue

Methods Endpoint/measurement parameters/methodology

Investigated system:

isolated organ

Time of investigation:

after exposure

Main outcome of study (acc. to author)

Study character:

medical/biological study
experimental study
full/main study

Study funded by

not stated/no funding

Titushkin IA et al. (2009): Altered Calcium Dynamics Mediates P19-Derived Neuron-Like Cell Responses to Millimeter-Wave Radiation

Platano D et al. (2007): Acute exposure to low-level CW and GSM-modulated 900 MHz radiofrequency does not affect Ba(2+) currents through voltage-gated calcium channels in rat cortical neurons

Blackman CF et al. (1989): Multiple power-density windows and their possible origin

Dutta SK et al. (1984): Microwave radiation-induced calcium ion efflux from human neuroblastoma cells in culture

Blackman CF et al. (1979): Induction of calcium-ion efflux from brain tissue by radio frequency radiation: Effects of modulation frequency and field strength