Study type: Medical/biological study (experimental study)

Effect of microwaves (2450-MHz) on the immune system in mice: studies of nucleic acid and protein synthesis. med./bio.

Published in: Bioelectromagnetics 1980; 1 (2): 161-170

Aim of study (acc. to author)

To evaluate whether the increased frequency of complement-receptor positive splenocytes (splenic cells) by microwave irradiation is associated with elevated nucleic acid and protein synthesis.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: continuous for 30 min ( 1 or 3 exposures)
  • SAR: 15 mW/g maximum (whole body) (12 - 15 mW/g (average))
  • SAR: 12 mW/g minimum (whole body)
  • power: 600 mW

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration continuous for 30 min ( 1 or 3 exposures)
Modulation
Modulation type CW
Exposure setup
Exposure source
Setup mice in transparent polystyrene holders were oriented with their heads towards the irradiation source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 15 mW/g maximum calculated whole body 12 - 15 mW/g (average)
SAR 12 mW/g minimum calculated whole body -
power 600 mW - - - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No significant differences between the incorporation of ³H-thymidine (DNA substrate), ³H-uridine (RNA substrate), and ³H-leucine (protein substrate) for microwave exposed and sham-exposed cultured cells were observed. A significant increase in the frequency of complement-receptor positive (CR+) splenocytes was observed. The increased number of CR+ splenocytes as a result of microwave exposure is not associated with significant changes in the rate of nucleic acid and protein synthesis in spleen cells, bone marrow, or peripheral blood lymphocytes.

Study character:

Study funded by

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