EMF-Portal | Effects of millimeter-wave radiation on monolayer cell cultures. III. A search for frequency-specific athermal biological effects on protein synthesis

Effects of millimeter-wave radiation on monolayer cell cultures. III. A search for frequency-specific athermal biological effects on protein synthesis med./bio.

By: Bush LG, Hill DW, Riazi A, Stensaas LJ, Partlow LM, Gandhi OP

Published in: Bioelectromagnetics 1981; 2 (2): 151-159

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Aim of study (acc. to author)

Background/further details

Protein synthesis was determined by measurement of optical densities of autoradiographes based on the incorporation of ³H-labeled methionine.

Endpoint

Exposure

Exposure	Parameters
Exposure 1: 38–48 GHz Modulation type: CW Exposure duration: 15 min	power density: 292 mW/cm² maximum
Exposure 2: 65–75 GHz Modulation type: CW Exposure duration: 15 min	power density: 177 mW/cm² maximum

Exposure 1

Main characteristics

Frequency	38–48 GHz
Type	electromagnetic field
Exposure duration	15 min
Additional info	0,1 GHz increments

Modulation

Modulation type	CW

Exposure setup

Exposure source	circular waveguide open end of a waveguide; aperture 3.1 x 1.55 mm
Sham exposure	A sham exposure was conducted.

Parameters

Measurand	Value	Type	Method	Mass	Remarks
power density	292 mW/cm²	maximum	-	-	-

Exposure 2

Main characteristics

Frequency	65–75 GHz
Type	electromagnetic field
Exposure duration	15 min
Additional info	0,1 GHz increments

Modulation

Modulation type	CW

Exposure setup

Exposure source	circular waveguide open end of a waveguide; aperture 4.8 x 2.4 mm
Sham exposure	A sham exposure was conducted.

Parameters

Measurand	Value	Type	Method	Mass	Remarks
power density	177 mW/cm²	maximum	-	-	-

Reference articles

Partlow LM et al. (1981): Effects of millimeter-wave radiation on monolayer cell cultures. I. Design and validation of a novel exposure system

Exposed system:

intact cell/cell culture
hamster/BHK-21 clone 13

Methods Endpoint/measurement parameters/methodology

Investigated system:

intact cell/cell culture

Time of investigation:

during exposure

Main outcome of study (acc. to author)

No evidence was found for frequency specific athermal biological effects or for the existence of an amplitude specific "power window".

Study character:

medical/biological study
experimental study
full/main study

Study funded by

National Cancer Institute (NCI; U.S. National Institutes of Health), Maryland, USA

U.S. Navy

Partlow LM et al. (1981): Effects of millimeter-wave radiation on monolayer cell cultures. I. Design and validation of a novel exposure system

Stensaas LJ et al. (1981): Effects of millimeter-wave radiation on monolayer cell cultures. II. Scanning and transmission electron microscopy

Effects of millimeter-wave radiation on monolayer cell cultures. III. A search for frequency-specific athermal biological effects on protein synthesis med./bio.

Aim of study (acc. to author)

Background/further details

Endpoint

Exposure

Exposure 1

Main characteristics

Modulation

Exposure setup

Parameters

Exposure 2

Main characteristics

Modulation

Exposure setup

Parameters

Reference articles

Methods Endpoint/measurement parameters/methodology

Main outcome of study (acc. to author)

Study funded by

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