Study type: Medical/biological study (experimental study)

Studies of the teratogenic potential of exposure of rats to 6000 MHz microwave radiation. I. Morphologic analysis at term med./bio.

Published in: Radiat Res 1984; 97 (2): 272-281

Aim of study (acc. to author)

To establish a near maximum power density level of microwave irradiation at 6000 MHz which does not cause a significant increase in body temperature in the pregnant rat, and to study if protracted exposure to that power density level throughout pregnancy would result in embryopathic effects.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 6 GHz
Exposure duration: continuous through pregnancy (21 days)

General information

The rats (n=36) were randomly assigned to one of the 4 groups: Group 1: home cage control (n=5), Group 2: anechoic chamber control (n=10), Group 3: sham irradiated concurrent control (n=10) and Group 4: irradiated (n=11).

Exposure 1

Main characteristics
Frequency 6 GHz
Type
Exposure duration continuous through pregnancy (21 days)
Exposure setup
Exposure source
Distance between exposed object and exposure source 2 m
Setup 648 cubic feet anechoic chamber lined with absorbent material, horn antenna at the ceiling of the chamber connected to waveguide
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power density 35 mW/cm² - - - -
SAR 7.28 W/kg average over mass calculated whole body -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • before exposure
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

Preliminary studies indicated that 35 mW/cm² at 6 GHz would be an appropriate power density level. Exposure for 5 hours to this level did not result in an increase in body temperature.
The exposed fetuses exhibited slight but statistically significant growth retardation at term. Maternal monocyte count was also significantly depressed. No other parameters differed between the control animals and the exposed animals.

Study character:

Study funded by

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