研究のタイプ: 疫学研究 (observational study)

[超低周波磁界への親の職業ばく露と小児白血病リスクとの関連] epidem.

Associations of parental occupational exposure to extremely low-frequency magnetic fields with childhood leukemia risk.

掲載誌: Leuk Lymphoma 2016; 57 (12): 2855-2862

この研究は、超低周波磁界(ELF-MF)への親の職業ばく露小児白血病リスクとの関連について一貫しない結果を提出しているこれまでの研究(症例対照研究11件、コホート研究1件)をプールして、メタ分析した。その結果、母親の職業ばく露も父親の職業ばく露小児白血病リスクとの関連を示さなかった;父親の職業ばく露に関しては、症例数の少ない研究または低品質の研究のみをプールした場合に有意な関連が見られたが、症例数の多い研究または高品質の研究のみをプールした場合には関連は確認されなかった、と報告している。

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研究の目的(著者による)

The association of parental occupational exposure to extremely low-frequency magnetic fields with childhood leukemia risk was investigated in a meta-analysis.

詳細情報

Following 12 studies were included: Shu et al. (1988), Infante-Rivard et al. (1991), Sorahan et al. (1999), Smulevich et al. (1999), Feychting et al. (2000), Infante-Rivard et al. (2003), McKinney et al. (2003), Ali et al. (2004), Pearce et al. (2007), Hug et al. (2010), Reid et al. (2011) and Keegan et al. (2012).

影響評価項目/リスク推定のタイプ

リスク推定のタイプ:

ばく露

調査対象集団

統計学的分析方法:

結論(著者による)

The overall results showed that neither maternal nor paternal occupational exposure to extremely low-frequency magnetic fields was associated with childhood leukemia risk (OR 1.01, CI 0.88-1.16).
In subgroup analysies of the paternal occupational exposure, significant association was found when pooling studies with small number of cases (OR 1.96, CI, 1.03-3.74) or with lower quality score (OR 1.52, CI, 1.07-2.15). However, this association was not confirmed when pooling studies with large number of cases or high quality score.
The authors conclude that the data indicate no association between parental occupational exposure to extremely low-frequency magnetic fields and childhood leukemia risk. The elevated odds ratios under certain subgroup analysis is likely due to chance.

研究助成

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