Study type: Epidemiological study

Magnetic fields exposure from high-voltage power lines and risk of amyotrophic lateral sclerosis in two Italian populations. epidem.

Published in: Amyotroph Lateral Scler Frontotemporal Degener 2017; 18 (7-8): 583-589

Aim of study (acc. to author)

A case-control study was conducted in Italy to investigate the association between residential exposure to magnetic fields from power lines and the risk of amyotrophic lateral sclerosis in two regions characterized by different environmental and life-style characteristics.

Endpoint/type of risk estimation

Type of risk estimation: (odds ratio (OR))

Exposure

Assessment

Exposure groups

Group Description
Reference group 1 magnetic flux density: < 0.1 µT
Group 2 magnetic flux density: 0.1 - < 0.2 µT
Group 3 magnetic flux density: 0.2 - < 0.4 µT
Group 4 magnetic flux density: ≥ 0.4 µT
Reference group 5 magnetic flux density: < 0.1 µT
Group 6 magnetic flux density: ≥ 0.1 µT

Population

Case group

Control group

Study size

Cases Controls
Total 718 2,872
Evaluable 703 2,737
Statistical analysis method: (adjustment: )

Conclusion (acc. to author)

Only 6 cases and 35 controls were exposed to calculated magnetic flux density of more than 0.1 µT.
Overall, no association between residential exposure to high-voltage power lines and the risk of amyotrophic lateral sclerosis was found (group 6: OR 0.65, CI 0.27–1.55). No dose-response relationship was observed in the groups 2, 3 and 4. These results were confirmed in subgroup analyses (e.g. age at onset, sex or length of exposure).
The authors conclude that the exposure to magnetic fields from power lines occurring in the general population is not associated with increased amyotrophic lateral sclerosis risk.

Study funded by

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