Study type: Medical/biological study (experimental study)

Lack of promoting effects of the electromagnetic near-field used for cellular phones (929.2 MHz) on rat liver carcinogenesis in a medium-term liver bioassay. med./bio.

Published in: Carcinogenesis 1998; 19 (2): 311-314

Aim of study (acc. to author)

To investigate the possible cancer promotion potential of local exposure to a pulse modulated 929.2 MHz electromagnetic near field on chemically (diethylnitrosamine)-initiated rat liver carcinogenesis employing a medium-term bioassay.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 929.2 MHz
Modulation type: pulsed
Exposure duration: repeated daily exposure, 90 min/day, 5 days a week, over 6 weeks
  • power: 0.52 W (antenna input)
  • SAR: 0.8 W/kg average over mass (whole body) (0.58-0.80 W/kg)
  • SAR: 2 W/kg maximum (partial body) (2.0-1.7 W/kg in the liver)
  • SAR: 72 W/kg maximum (whole body) (7.2-6.6 W/kg)

Exposure 1

Main characteristics
Frequency 929.2 MHz
Type
Charakteristic
Exposure duration repeated daily exposure, 90 min/day, 5 days a week, over 6 weeks
Modulation
Modulation type pulsed
Duty cycle 33 %
Repetition frequency 50 Hz
Additional info

PDC modulation (Japanese Personal Digital Cellular standard)

Exposure setup
Exposure source
Distance between exposed object and exposure source 1 cm
Chamber A total of 12 exposure boxes with the antenna located at the centre of the bottom were placed in separate rooms.
Setup Animals were held individually in narrow plastic cylinders of 55 mm or 70 mm diameter with ventilation holes. Two cylinders were placed on either side of the antenna.
Additional info Animals were given a single injection of diethylnitrosamine two weeks before exposure to initiate hepatocarcinogenesis. Animals for sham exposure were treated the same way as animals in the exposure group but without EMF. Animals in the control group were not placed in the cylinders or exposure boxes.
Parameters
Measurand Value Type Method Mass Remarks
power 0.52 W - - - antenna input
SAR 0.8 W/kg average over mass - whole body 0.58-0.80 W/kg
SAR 2 W/kg maximum - partial body 2.0-1.7 W/kg in the liver
SAR 72 W/kg maximum cf. remarks whole body 7.2-6.6 W/kg

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

The study does not show any significant effect on rat liver carcinogenesis under the experimental present conditions.

Study character:

Study funded by

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