Study type: Medical/biological study (experimental study)

Lack of microbial genetic response to 2.45-GHz CW and 8.5- to 9.6-GHz pulsed microwaves. med./bio.

Published in: J Microw Power 1979; 14 (3): 275-280

Aim of study (acc. to author)

To test the mutagenic potential of microwaves, two single-cell biological systems with different degrees of genomic complexity were used: 1) Salmonella typhimurium, which is used widely to test for genetic mutations caused by base-pair substitutions and frame-shift alterations. 2) Saccharomyces cerevisiae, which is a primitive eukaryote having a more complex genome than the bacterium, what allows the testing of gene conversion and mitotic recombination.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: 90 min or 2 h
Exposure 2: 8.5–9.6 GHz
Modulation type: pulsed
Exposure duration: 90 min or 2 h

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Polarization
Exposure duration 90 min or 2 h
Modulation
Modulation type CW
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power density 1 mW/cm² minimum - - -
power density 45 mW/cm² maximum - - -

Exposure 2

Main characteristics
Frequency 8.5–9.6 GHz
Type
Polarization
Exposure duration 90 min or 2 h
Modulation
Modulation type pulsed
Duty cycle 0.1 %
Repetition frequency 1,000 Hz
Pulse type rectangular
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power density 1 mW/cm² minimum - - -
power density 45 mW/cm² maximum - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The results revealed no increase in mutations or of mitotic gene conversions when cells were exposed for two hours or less. Decreased viability of cells was noted in all cultures tested after exposure at the higher intensities of radiation. However, no reliable changes in genetic events occured.

Study character:

Study funded by

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