Study type: Medical/biological study (experimental study)

Effects of radiofrequency radiation on rabbit kidney: a morphological and immunological study med./bio.

By: Accinni L, De Martino C, Mariutti G
Published in: Exp Mol Pathol 1988; 49 (1): 22-37
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Aim of study (acc. to author)

To investigate possibel acute and chronic effects of 27.12 MHz radio frequency exposure in vivo on rabbit kidney by morphological and immunohistological techniques.

Background/further details

Fourteen rabbits were exposed while four unexposed animals served as control. Each half of the animals were examined direct after or five month after exposure, respectively.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 27.12 MHz
Exposure duration: 3 weeks; 5 consecutive days per week; 10 min the first day; 15 min the second day; 20 min the third, fourth and fitfth day

Exposure 1

Main characteristics
Frequency 27.12 MHz
Type
Exposure duration 3 weeks; 5 consecutive days per week; 10 min the first day; 15 min the second day; 20 min the third, fourth and fitfth day
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 1,100 V/m maximum measured - empty cage: 800 - 1100 V/m
magnetic field strength 3 A/m maximum measured - empty cage: 1.5 - 3 A/m
Additional parameter details

doses in the range of generally used human diathermy

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Immediately after exposure, focal tubular necrosis and focal and segmental glomerular sclerosis were observed at the rabbit kidneys and evolved into a membranous nephropathy in a few month. The mechanism by which the applied exposure conditions induced these changes is not clear.

Study character:

Study funded by

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