Study type: Medical/biological study (experimental study)

Interaction of low level modulated RF radiation with Na+-K+-ATP-ase. med./bio.

Published in: Bioelectrochem Bioenerg 1998; 47 (1): 247-252

Aim of study (acc. to author)

The effect of low level amplitude modulated radiofrequency radiation is examined on sodium potassium ATPase (Na+-K+-ATPase) activity in the developing rat brain.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 147 MHz
Modulation type: AM
Exposure duration: 20-60 min for short duration exposure or 3 h/day for 30-35 days
Exposure 2: 73.5 MHz
Modulation type: AM
Exposure duration: 20-60 min for short duration exposure or 3 h/day for 30-35 days
Exposure 3: 36.75 MHz
Modulation type: AM
Exposure duration: 20-60 min for short duration exposure or 3 h/day for 30-35 days

Exposure 1

Main characteristics
Frequency 147 MHz
Type
Exposure duration 20-60 min for short duration exposure or 3 h/day for 30-35 days
Modulation
Modulation type AM
Modulation frequency 16–76 Hz
Additional info

80-90% modulation depth

Exposure setup
Exposure source
Chamber Plexiglass cage/ 32 cm x 10 cm x 9 cm
Additional info cages kept in a TEM cell/ 115 cm long x 30 cm wide
Parameters
Measurand Value Type Method Mass Remarks
SAR 9.65 mW/g mean cf. remarks cf. remarks 6.11 W/kg
power density 14.7 W/m² mean cf. remarks - -

Exposure 2

Main characteristics
Frequency 73.5 MHz
Type
Exposure duration 20-60 min for short duration exposure or 3 h/day for 30-35 days
Modulation
Modulation type AM
Modulation frequency 16–76 Hz
Additional info

80-90% modulation depth

Exposure setup
Exposure source
Additional info same as in exposition 1
Parameters
Measurand Value Type Method Mass Remarks
SAR 9.65 mW/g mean cf. remarks cf. remarks 6.11 W/kg
power density 14.7 W/m² mean cf. remarks - -

Exposure 3

Main characteristics
Frequency 36.75 MHz
Type
Exposure duration 20-60 min for short duration exposure or 3 h/day for 30-35 days
Modulation
Modulation type AM
Modulation frequency 16–76 Hz
Additional info

80-90% modulation depth

Exposure setup
Exposure source
Additional info same as in exposition 1
Parameters
Measurand Value Type Method Mass Remarks
SAR 9.65 mW/g mean cf. remarks cf. remarks 6.11 W/kg
power density 14.7 W/m² mean cf. remarks - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The results show a significant increase of sodium potassium ATPase (Na+-K+-ATPase) activities in chronically exposed rat brains compared to control ones. With the irradiated groups, the data show relatively higher activities of Na+-K+-ATPase in rat brain exposed to different carrier wave frequencies amplitude modulated at 16 Hz compared to animals brain chronically exposed to same set of carrier wave frequencies AM at 76 Hz. However, the difference is statistically insignificant.
The increase in Na+-K+-ATPase activity in animals chronically exposed to AM at 16 and 76 Hz, respectively was independent of carrier wave frequencies.
Brain membranes from various irradiated groups were again exposed in vitro to their respective fields for 20-60 min and Na+-K+-ATPase activity was determined in each group. No statistically significant effect on enzyme activity was observed.

Study character:

Study funded by

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