Study type: Medical/biological study (experimental study)

Effect of controlled electromagnetic radiation on the growth of cells in tissue culture. med./bio.

Published in: J Surg Res 1979; 27 (1): 8-13

Aim of study (acc. to author)

To investigate the effects of 2450 MHz microwave exposure on the growth of different mammalian cell lines and six different bacterial strains.

Background/further details

Investigated mammalian cell lines were VX2, RT, L-929, and L60T.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Exposure duration: 5 times for 1 min each
-

Exposure 1

Main characteristics
Frequency 2.45 GHz
Exposure duration 5 times for 1 min each
Exposure setup
Exposure source
Setup Cells were exposed in scintillation vails which were supported by a polystyrene table which turns at a constant speed of 23 rpm.
Parameters

No parameters are specified for this exposure.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The growth of L-929 cells was significantly decreased by microwave exposure and microscopic analysis revealed lysis and cellular disruption.
The effects of microwave exposure in context with cell cycle was studied on L60T cells. No effects were observed on cells in S phase and G1 phase whereas growth of cells in mitosis phase as well as in G2 phase was decreased due to microwave exposure.
Preliminary experiments on VX2 and RT cell lines indicate that these cells are more sensitive to microwave exposure than the L-cell lines.
No alterations on the growth of the investigated six different bacterial strains (Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa) were observed.

Study character:

Study funded by

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