poly(ADP-ribose) polymerase

Synonyms:
  • PARP
  • poly ADPR polymerase
German: Poly-(ADP-Ribose)-Polymerase
Japanese: ポリ(ADP-リボース)ポリメラーゼ

Enzymology. An enzyme involved in many cellular processes such as DNA repair and programmed cell death. It catalyzes the transfer of multiple ADP-ribose groups from NAD+ onto substrate proteins, thus building up a linear or branched homopolymer of repeating ADP-ribose units.

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