Study type: Medical/biological study (experimental study)

Micronuclei in peripheral blood and bone marrow cells of mice exposed to 42 GHz electromagnetic millimeter waves. med./bio.

Published in: Radiat Res 2004; 161 (3): 341-345

Aim of study (acc. to author)

To study the genotoxic potential of 42.2 GHz electromagnetic millimeter waves in mice.

Background/further details

Groups of animals that were injected with cyclophosphamide (15 mg/kg body weight), a drug used in the treatment of human malignancies, were also included to examine if millimeter wave irradiation had any influence on drug-induced genotoxicity.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 42.2 GHz
Exposure duration: repeated daily exposure, 30 min/day for 3 consecutive days

Exposure 1

Main characteristics
Frequency 42.2 GHz
Charakteristic
Exposure duration repeated daily exposure, 30 min/day for 3 consecutive days
Modulation
Modulation type cf. additional info
Additional info

The signal was 100% modulated with a half wave rectified 60 Hz sine wave.

Exposure setup
Exposure source
Distance between exposed object and exposure source 0.005 m
Setup The animals were restrained in individual high density polypropylene centrifugal tubes with a 9 mm-diameter opening in which the nose was stuck. The antenna was positioned 5 mm from the tip of the horn.
Parameters
Measurand Value Type Method Mass Remarks
power density 315 W/m² mean calculated - -
SAR 622 W/kg mean calculated unspecified -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data showed that the incidence of micronuclei in 2000 polychromatic erythrocytes was not significantly different among untreated, exposed, and sham-exposed mice. Mice that were injected with cyclophosphamide exhibited significantly increased numbers of micronuclei. The drug-induced micronuclei were not significantly different in exposed and sham-exposed mice. Thus there was no evidence for the induction of genotoxicity in the peripheral blood and bone marrow cells of mice exposed to electromagnetic millimeter waves. Also, millimeter wave exposure did not influence cyclophosphamide-induced micronuclei in either type of cells.

Study character:

Study funded by

Related articles