Groups of animals that were injected with cyclophosphamide (15 mg/kg body weight), a drug used in the treatment of human malignancies, were also included to examine if millimeter wave irradiation had any influence on drug-induced genotoxicity.
The data showed that the incidence of micronuclei in 2000 polychromatic erythrocytes was not significantly different among untreated, exposed, and sham-exposed mice. Mice that were injected with cyclophosphamide exhibited significantly increased numbers of micronuclei. The drug-induced micronuclei were not significantly different in exposed and sham-exposed mice. Thus there was no evidence for the induction of genotoxicity in the peripheral blood and bone marrow cells of mice exposed to electromagnetic millimeter waves. Also, millimeter wave exposure did not influence cyclophosphamide-induced micronuclei in either type of cells.