The effects of exposure of canine kidney cells to a 50 Hz magnetic field on the quantity and localization of some junctional proteins of adherens and tight junctions should be investigated.
Adherens and tight junctions are sensitive to heat generated by radio frequency fields. However, non-thermal effects are still unclear, so this study was conducted.
Cells were either not exposed (control group) or exposed for 4 (exposure group 1) or 24 h (exposure group 2).
| Exposure | Parameters |
|---|---|
|
Exposure 1:
50 Hz
Exposure duration:
continuous for 4 or 24 h
|
|
| Frequency | 50 Hz |
|---|---|
| Type | |
| Exposure duration | continuous for 4 or 24 h |
| Exposure source | |
|---|---|
| Setup | a pair of Helmholtz coils with an inner diameter of 12 cm and 85 turns of 0.3 mm copper wire each was placed inside a CO2 incubator with a constant temperature of 37°C; a vertical magnetic field was produced |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| magnetic flux density | 500 µT | effective value | measured | - | - |
The location of all investigated proteins was not changed in both exposure groups compared to control, but the amount of membrane-bound proteins seemed to be higher. The total amount of β-catenin was significantly decreased in both exposure groups compared to the control.
The authors conclude that exposure of canine kidney cells to a 50 Hz magnetic field might affect the local and total amount of some junction proteins in cells.
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