Study type: Medical/biological study (experimental study)

The effect of extremely low-frequency electromagnetic fields on skin and thyroid amine- and peptide-containing cells in rats: an immunohistochemical and morphometrical study. med./bio.

Published in: Environ Res 2005; 99 (3): 369-377

Aim of study (acc. to author)

To study the influence of extremely low frequency electromagnetic fields on mast cells, parafollicular cells, and nerve fibers in rat skin and thyroid gland.



Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: repeated daily exposure, 4 h/day, 7 days a week for 1 month

Exposure 1

Main characteristics
Frequency 50 Hz
Exposure duration repeated daily exposure, 4 h/day, 7 days a week for 1 month
Exposure setup
Exposure source
Distance between exposed object and exposure source 12 cm
Setup Cages were placed on both sides of the coil, perpendicular to the coil axis.Control animals were handled in the same manner as the exposed ones and were maintained in a similar environment but in the absence of EMF.
Additional info The axis was parallel to the lines of force of the geomagnetic field (north-south direction).
Measurand Value Type Method Mass Remarks
electric field strength 160 V/m unspecified measured - to 54 V/m
magnetic flux density 300 µT maximum measured - on the side of the cage near the coil
magnetic flux density 100 µT minimum measured - on the side of the cage opposite to the coil

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

A significantly increased number of serotonin-positive mast cells in the skin and neuropeptide Y-containing nerve fibers in the thyroid of rats exposed to extremely low frequency electromagnetic fields was revealed compared to controls, indicating a possible electromagnetic field effect on skin and thyroid vasculature.

Study character:

Study funded by

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