Study type: Medical/biological study (experimental study)

Effects of extremely-low-frequency pulsed electromagnetic fields on collagen synthesis in rat skin. med./bio.

Published in: Biotechnol Appl Biochem 2006; 43 Pt 2: 71-75

Aim of study (acc. to author)

To investigate the effects of extremely low frequency pulsed electromagnetic fields on the synthesis of epidermal collagen.

Background/further details

8 male rats per treatment group were examined.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 25 Hz
Modulation type: pulsed
Exposure duration: 2.5 h / day for 8 days
Exposure 2: 50 Hz
Modulation type: pulsed
Exposure duration: 2.5 h / day for 8 days
Exposure 3: 100 Hz
Modulation type: pulsed
Exposure duration: 2.5 h / day for 8 days

Exposure 1

Main characteristics
Frequency 25 Hz
Type
Waveform
Exposure duration 2.5 h / day for 8 days
Modulation
Modulation type pulsed
Exposure setup
Exposure source
Setup a pair of Helmholtz coils with a diameter of 75 cm, 35 cm apart ; the plexiglas housing for the animals was placed in the center of the coils
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 4 mT - - - -
magnetic flux density 2 mT - - - -
magnetic flux density 1 mT - - - -

Exposure 2

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration 2.5 h / day for 8 days
Modulation
Modulation type pulsed
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2 mT - - - -

Exposure 3

Main characteristics
Frequency 100 Hz
Type
Waveform
Exposure duration 2.5 h / day for 8 days
Modulation
Modulation type pulsed
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2 mT - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The results indicated that a pulsed electromagnetic field of 2 and 4 mT at 25 Hz increased the collagen synthesis. The other intensities and frequency setting did not have any noticeable effect.

Study character:

Study funded by

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