Pro-oxidant effects of extremely low frequency 50 Hz magnetic fields were investigated in the land snail Helix aspersa exposed both in short-term laboratory treatments and under field conditions by maintaining the animals in the proximity of a power line for up to 2 months
Exposure duration: continuous for 10 days
Exposure duration: continuous for 10, 20, 40, and 60 days
|Exposure duration||continuous for 10 days|
|Setup||Exposure was carried out in a Helmholtz coil chamber (100 cm in diameter) with two solenoids producing a highly homogeneous field. During exposures, snails were maintained in plastic cages inside the Helmholtz coil system.|
|Additional info||Background environmental field measured was lower than 0.1 µT.|
|Exposure duration||continuous for 10, 20, 40, and 60 days|
The data indicated an oxidative challenge caused by extremely low frequency magnetic fields with prompt and sensitive responses for catalase, glutathione reductase, and the overall capability to neutralize peroxyl radicals. Cell injuries occurred to different extents according to intensity and duration of extremely low frequency magnetic field exposure and confirmed complex cause-effect relationships between pro-oxidant factors, efficiency of antioxidant defenses, and the onset of oxidative toxicity.
This study highlights the importance of a multimarker approach for detecting a wide panel of biological responses and the necessity of investigating the long-term effects of early oxidative responses.