Study type: Medical/biological study (experimental study)

Effects of prooxidants on human serum exposed to 50 Hz magnetic fields. med./bio.

Published in: Electromagn Biol Med 2007; 26 (2): 135-140

Aim of study (acc. to author)

This in vitro study should clarify whether the exposure to extremely low frequency magnetic fields induces alterations in free radical formation in human serum.

Background/further details

The sera of a 34 year old woman and a 40 year old man, both non smoker and healthy, were used. Additionally, the oxidants iron (II)-chloride (FeCl2) and H2O2 were applied in three different concentrations (1 µM, 5 µM, 10 µM).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 1 h
Exposure 2: 50 Hz
Exposure duration: continuous for 1 h or 2 h

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Exposure duration continuous for 1 h
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.357 mT - - - -
magnetic flux density 0.596 mT - - - -
magnetic flux density 1.788 mT - - - -
magnetic flux density 2.384 mT - - - -

Exposure 2

Main characteristics
Frequency 50 Hz
Type
Exposure duration continuous for 1 h or 2 h
Additional info prooxidants FeCl2 and H2O2 in different concentrations added
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.357 mT - - - for the female serum
magnetic flux density 2.384 mT - - - for the male serum

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • before exposure
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

Female and male serum behaved in different manner due to exposure. Whereas male serum showed increasing chemiluminescence with increasing magnetic flux densities, the maximal chemiluminescence in female serum was observed at minimum magnetic flux density.
The treatment with the oxidants increased the chemiluminescence even more. Whereas magnetic field exposed serum of the man exhibited increased chemiluminescence with increasing oxidant concentrations (FeCl2 more pronounced than H2O2), one hour exposed serum of the woman behaved vice versa.

Study character:

Study funded by

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