Study type: Medical/biological study (experimental study)

Low-frequency magnetic field effect on cytoskeleton and chromatin. med./bio.

Published in: Bioelectrochemistry 2007; 70 (1): 96-100

Aim of study (acc. to author)

This study was performed to examine the effects of low frequency magnetic field on cytoskeleton and chromatin structure of human lung carcinoma cells in vitro.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 96 h

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Exposure duration continuous for 96 h
Exposure setup
Exposure source
Setup The Petri dishes (30 mm in diameter) were placed in the coil on a non-conducting stand where the field uniformity deviated about 3%. The control samples were kept under the same conditions without magnetic field.
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2 mT mean unspecified - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Slight morphological changes of F-actin filaments arrangement and mitochondria distribution were observed in magnetic field exposed cells and nuclear chromatin condensation was found. These changes were associated with apoptosis induced by the exposure to magentic field.
No statistically significant changes were found in the chromatin arrangement around the centromere.

Study character:

Study funded by

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