To test the hypothesis that radiofrequency or 60 Hz exposures reduce melatonin and increase estrogen production, the authors measured a urinary metabolite of each hormone among women living in a community with increased radiofrequency power densities from nearby radio and TV broadcasting antennae.
A total of 127 women aged 12 to 81 years participated. Each woman was studied for a 2.5-day period beginning in the evening on the initial day and ending in the morning on the final day. Each subject collected one overnight urine sample immediately after their first night of participation and a second overnight sample on their final participation night.
|Exposure 1: 0.1–3,000 MHz|
|Exposure 2: 60 Hz|
The study area, participant population, and RF exposure characteristics have been described in [Burch et al., 2006]. Exposure assessment included RF spot measurements inside and outside the home, and continuous personal monitoring for 60-Hz magnetic field and ambient light exposures. Participants were recruited from 161 residences with high (>4.0 µW/cm²), medium (0.5 to 4.0 µW/cm²), or low (<0.5 µW/cm²) RF exposures.
An association between radiofrequency and 60 Hz exposures and increased estrone-3-glucuronide excretion was observed among postmenopausal but not premenopausal women. This association was strongest among postmenopausal women with low 6-hydroxymelatoninsulfate levels. Women with reduced nocturnal 6-hydroxymelatoninsulfate excretion may represent a sensitive subgroup.