To study the influence of different shapes of low frequency magnetic field exposures (sinusoidal, rectangular, triangular) on enzyme activities of catalase and superoxide dismutase, malondialdehyde concentration and free radicals generation in human blood platelets.
The formation of free radicals, the concentration of malondialdehyde and the enzyme activity of catalase showed increased values compared with the initial levels, regardless of the shape of the magnetic field applied. The highest increase of free radical formation in relation to the initial value was found after exposure to the triangular magnetic field. Catalase enzyme activity also depended on the shape of the magnetic field: The highest increase was found after application of the triangular field, whereas the lowest one was observed when the sinusoidal magnetic field was applied. The highest increase of malondialdehyde concentration was found after sinusoidal magnetic field exposure compared to control.
Superoxide dismutase enzyme activity decreased after exposure and the enzyme activity depended on the shape of the magnetic field: The highest decrease, compared to the initial values, was observed when platelets were exposed to a magnetic field of triangular and rectangular shape.
The date indicate that the oxidative stress resulting from exposure to 50 Hz magnetic field may produce a number of adverse effects within the cell. Additionally, the findings point at the significance of the shape of the magnetic field.