Study type: Medical/biological study (experimental study)

Aneuploidy studies in human cells exposed in vitro to GSM-900 MHz radiofrequency radiation using FISH. med./bio.

Published in: Int J Radiat Biol 2011; 87 (4): 400-408

Aim of study (acc. to author)

To study whether radiofrequency exposure similar to that emitted by GSM mobile phones may induce aneuploidy in cultured human amniotic cells.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 24 h
  • SAR: 4 W/kg spatial average (0.25, 1, 2, 4 W/kg)
  • SAR: 32 W/kg peak value (2, 8, 16, 32 W/kg)

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration continuous for 24 h
Modulation
Modulation type pulsed
Pulse width 0.577 ms
Repetition frequency 217 Hz
Exposure setup
Exposure source
  • signal generator RFS900-60 + modulating unit RFPA
Setup samples placed in eight 35 mm Petri dishes, each inside a 50 mm Petri dish; dishes positioned in a 15 cm x 15 cm wire-patch cell inside a box with absorbing walls of ferrite; exposure and sham exposure boxes kept in the same incubator
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 4 W/kg spatial average calculated - 0.25, 1, 2, 4 W/kg
SAR 32 W/kg peak value calculated - 2, 8, 16, 32 W/kg

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No significant change in the rate of aneuploidy of chromosomes 11 and 17 was found following exposure to GSM-900 for 24 h at average SAR up to 4 W/kg. In conclusion, the data did not show any in vitro aneuploidogenic effect of GSM.

Study character:

Study funded by

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