Study type: Medical/biological study (experimental study)

Exposure of human peripheral blood lymphocytes to electromagnetic fields associated with cellular phones leads to chromosomal instability. med./bio.

Published in: Bioelectromagnetics 2003; 24 (2): 82-90

Aim of study (acc. to author)

To address the question whether in vitro exposure of human peripheral blood lymphocytes to mobile telephone frequencies (continuous 830 MHz) leads to genetic effects that are associated with increased risk for cancer.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 830 MHz
Modulation type: CW
Exposure duration: continuous for 72 h
  • power: 1 W maximum
  • SAR: 2 W/kg mean (unspecified) (± 0.3 W/kg)
  • SAR: 2.9 W/kg mean (unspecified) (± 0.3 W/kg)
  • SAR: 4.3 W/kg mean (unspecified) (± 0.2 W/kg)
  • SAR: 8.2 W/kg mean (unspecified) (± 0.6 W/kg)

Exposure 1

Main characteristics
Frequency 830 MHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 72 h
Modulation
Modulation type CW
Exposure setup
Exposure source
  • parallel plate RF resonator, 6 cm long, 5 cm wide and 2.4 cm apart
Chamber incubator
Setup The exposure cell consisted of a plastic standard tissue culture flask of 25 cm² that was placed within a parallel plate RF resonator fed by a coaxial cable through a tapered transition section.
Additional info The sham exposed sample was placed in the same incubator, at a different height level, with a metal plate between the two samples. An additional control flask was grown in a different incubator which was set to 37 °C.
Parameters
Measurand Value Type Method Mass Remarks
power 1 W maximum measured - -
SAR 2 W/kg mean measured and calculated unspecified ± 0.3 W/kg
SAR 2.9 W/kg mean measured and calculated unspecified ± 0.3 W/kg
SAR 4.3 W/kg mean measured and calculated unspecified ± 0.2 W/kg
SAR 8.2 W/kg mean measured and calculated unspecified ± 0.6 W/kg

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The results indicate that human cells exposed to radiofrequency radiation acquire premalignant genotypes associated with elevated levels of aneuploidy and abnormalities in replication mode as expressed in asynchrony in the replication timing of homologous chromosomal regions associated with chromosome segregation.

Study character:

Study funded by

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