Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells.
Published in: PLoS One 2011; 6 (12): e28474
Aim of study (acc. to author)
CDMA mobile communications
continuous for 1 h or 3 h
continuous for 1 h/day for 7 days
rectangular cavity-type chamber in TE
102 mode; monopole antenna positioned at λ/8 position at the cavity's top plate; cells placed at λ/4 position in the chamber in 100 mm-dishes with a layer thickness of 4 mm; chamber equipped with a cooling device
sham exposure was conducted.
Lee JS et al.
Radiofrequency radiation does not induce stress response in human T-lymphocytes and rat primary astrocytes.
molecular biosynthesis: hair cell growth related gene expression in the cell cultures (VEGF ( vascular endothelial growth factor A), HGF ( hepatocyte growth factor), IGF-1 ( insulin-like growth factor), TGF-beta1; RT-PCR) and protein expression in the cells (targets of IGF-1: MAPK-1, p- MAPK-1, Bcl-2, Bax, cyclin-D1; Western blot), oxidative stress in the cells ( reactive oxygen species production; via dichlorofluorescein diacetate; flow cytometry)
cell viability/ cell division/ proliferation: cell proliferation in the preparations ( ex vivo Ki-67 antigen immunofluorescence staining), apoptosis in the preparations ( ex vivo TUNEL assay); cell cycle distributions in the cell preparation ( propidium iodide staining, flow cytometry) hair
growth (hair ex vivo follicle elongation ( stereo microscopy), Main outcome of study (acc. to author)
Study funded by
Korea Communications Commission (KCC), Korea
Ministry of Education, Science and Technology (MEST), Korea
Korea Communications Agency (KCA), Korea
National Research Foundation (NRF) of Korea
Li X et al.
Exposure to 50 Hz electromagnetic fields enhances hair follicle regrowth in C57BL/6 mice.
Galloni P et al.
No effects of UMTS exposure on the function of rat outer hair cells
Huang TQ et al.
Characterization of biological effect of 1763 MHz radiofrequency exposure on auditory hair cells.
Maddin WS et al.
The biological effects of a pulsed electrostatic field with specific reference to hair. Electrotrichogenesis.