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Medical/biological study (experimental study)

Toxic effects of 50 Hz electromagnetic field on memory consolidation in male and female mice.

Published in: Toxicol Ind Health 2013; 29 (3): 293-299

Aim of study (acc. to author)

To study the effect of extremely low frequency magnetic fields (50 Hz) on memory consolidation in adult male and female mice.
Background/further details: 30 male and 30 female mice were divided into six groups (each group n=10): two exposure groups, two sham exposure groups and two control groups. Mice were exposed immediately after the "learning session" of the passive avoidance test. Tests were repeated 24 h after the learning session.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for four hours
General information
Male and female mice were divided into six groups; the follwing groups consisted of each one male and one female group: i) exposure group ii) sham exposure group iii) control group
Exposure 1
Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration continuous for four hours
Exposure setup
Exposure source
Setup characteristics of round coil: 1000 turns, copper wire (0,5 mm); dissipation of generated heat due to good ventilation in exposure area
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 8 mT - calibration - at the center of the coil
Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated material:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data showed that the exposure to an 8 mT, 50 Hz magnetic field for 4 h had adverse effects on memory consolidation in male and female mice (significant decreases in memory function: step-down latency lower).
Study character:

Study funded by

  • not stated/no funding

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