To determine if 1) radiofrequency radiation (RFR) alone (2450 MHz, pulsed wave) can induce sister chromatid exchange (SCE) formation in Chinese hamster ovary cells, and 2) RFR during simultaneous treatment with mitomycin C (MMC) under the same conditions can cause a change in frequency in SCEs beyound that which is produced by the MMC alone.
|Exposure duration||up to 3 h|
|Pulse width||10 µs|
|Duty cycle||25 %|
|Repetition frequency||25 kHz|
1) Pulsed wave RFR at the specific field parameters (i.e. at a moderate power density and SAR) has no effect on sister chromatid exchange (SCE) induction in CHO cells, and is unlikely to be genotoxic. 2) A simultaneous treatment with MMC and RFR did nor result in an increase SCE frequency over that caused by MMC treatment alone.