Study type: Epidemiological study (observational study)

Effect of mobile phones on micronucleus frequency in human exfoliated oral mucosal cells. epidem.

Published in: Oral Dis 2012; 18 (8): 786-792

Aim of study (acc. to author)

A cohort study was conducted in Spain to investigate the genotoxic effects of mobile phones on oral mucosal cells of healthy persons.

Further details

Two cell samples of buccal mucosa were collected from the right and left cheeks of the 50 subjects. The exposed cheek was defined as the cheek where the mobile phone was preferentially placed during calls, the other cheek was defined as unexposed. The cell samples were stained with the dye DAPI and microscopically examined to detect DNA damage and cytokinetic defects (micronuclei and binucleated cells), proliferation, and cell death.

Endpoint/type of risk estimation

Exposure

Assessment

Exposure groups

Group Description
Group 1 mobile phone use per week: 0 - 3 h
Group 2 mobile phone use per week: 3 - 6 h
Group 3 mobile phone use per week: 6 - 9 h
Group 4 mobile phone use per week: 9 - 12 h
Group 5 mobile phone use per week: 12 - 15 h
Group 6 overall mobile phone use: < 5 years
Group 7 overall mobile phone use: 5 - 10 years
Group 8 overall mobile phone use: > 15 years
Group 9 preferential side of the face at which the mobile phone is placed: right
Group 10 preferential side of the face at which the mobile phone is placed: left

Population

Study size

Type Value
Total 50

Conclusion (acc. to author)

No statistically significant changes were found in exposed buccal mucosa cell samples compared to non-exposed buccal mucosa in healthy persons.
The authors conclude that no genotoxic effects due to mobile phone exposure were observed.

Study funded by

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