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Medical/biological study (observational study)

A Preliminary Study to Assess Possible Chromosomal Damage Among Users of Digital Mobile Phones.

Published in: Electromagn Biol Med 2003; 22 (2-3): 149-159

Aim of study (acc. to author)

To assess chromosome aberrations and sister chromatid exchange frequencies among users who used digital mobile phones frequently for a maximum period of 4-5 hours a day, continuously for 2 years (non-smoker-nonalcoholic subjects and smoker-alcoholics). In addition blood samples were treated with the known mutagen mitomycin C to find out comutagenic/synergistic effect.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 890–960 MHz
Modulation type: pulsed
Exposure duration: average 1 to 3 or 3 to 5 hours per day for at least 2 years
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General information
48 individuals were selected for blood sample work-up. Half of the subjects selected used mobile phones over at least 2 years which employed GMSK modulations at uplink frequencies of 935 to 960 MHz and downlinks at 890 to 915 MHz and the other half served as control.
Exposure 1
Main characteristics
Frequency 890–960 MHz
Exposure duration average 1 to 3 or 3 to 5 hours per day for at least 2 years
Modulation
Modulation type pulsed
Pulse width 0.577 ms
Repetition frequency 217 Hz
Additional info FDMA consisting of 124 channels, each channel has 200 kHz. Within 200 kHz, TDMA frame duration of 4.615 msec and burst period of 0.577 ms.
Exposure setup
Exposure source
Parameters
No parameters are specified for this exposure.
Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated material:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

There was a significant increase in dicentric chromosomes among mobile phone users who were smoker-alcoholic as compared to their controls; similarly, a significant increase in dicentric chromosomes was revealed in smoker-alcoholic mobile phone users in comparison to nonsmoker and nonalcoholic mobile phone users. After mitomycin C treatment of blood samples, there was a significant increase in dicentric chromosomes and ring chromosomes in both smoker-alcoholic and nonsmoker-nonalcoholic groups.
Study character:

Study funded by

  • not stated/no funding

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