Study type: Medical/biological study (experimental study, observational study)

Cytogenetic investigation of subjects professionally exposed to radiofrequency radiation. med./bio.

Published in: Mutagenesis 2006; 21 (2): 139-142

Aim of study (acc. to author)

To study cytogenetic effects in peripheral blood lymphocytes from 49 subjects who were professionally exposed to mobile phone electromagnetic fields (radio field engineers and other subjects working for two of the Belgian mobile phone operators).

Background/further details

Subjects' blood cells were also exposed to mutagen mitomycin C in order to investigate possible combined effects of radiofrequency irradiation and the chemical.
The data were compared to those obtained in 25 unexposed control subjects.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 450–900 MHz
Exposure duration: repeated daily exposure, at least 1 h/day for 2.3 years (on average)
-
Exposure 2: 147.25 MHz–40 GHz
Exposure duration: repeated daily exposure during work
-

General information

Test persons worked for two companies: company 1: 27 radio field engineers company 2: 11 radio field engineers, 11 administrative workers.

Exposure 1

Main characteristics
Frequency 450–900 MHz
Type
Exposure duration repeated daily exposure, at least 1 h/day for 2.3 years (on average)
Additional info 450 and 900 MHz and other frequencies in the MHz or GHz range
Exposure setup
Exposure source
Distance between exposed object and exposure source 1 m
Additional info The radio field engineers worked in the maintenance and repair of transmission antennas that were normally switched off for this purpose.
Parameters

No parameters are specified for this exposure.

Exposure 2

Main characteristics
Frequency 147.25 MHz–40 GHz
Type
Exposure duration repeated daily exposure during work
Exposure setup
Exposure source
Additional info The administrative staff worked in buildings that were surrounded by RF-dipole antennas operating at 147.25, 164.35, and 169.625 MHz and parabolic antennas with frequencies between 6 and 40 GHz.
Parameters

No parameters are specified for this exposure.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The comet assay, sister chromatid exchange and chromosome aberration tests revealed no evidence of radiofrequency-induced genetic effects.
No cooperative action was found between the electromagnetic field exposure of blood cells and the mutagen using either the comet assay or sister chromatid exchange test.

Study character:

Study funded by

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