Study type: Medical/biological study (observational study)

Is human saliva an indicator of the adverse health effects of using mobile phones? med./bio.

Published in: Antioxid Redox Signal 2013; 18 (6): 622-627

Aim of study (acc. to author)

The study compared salivary secretion, focusing on various salivary components and oxidative stress indices, between users of mobile phones and non-users.

Background/further details

20 subjects (10 men, 10 women) served as "mobile phone exposure group" and had a mean duration of mobile phone use of 12.5 years (range 8-15) and a mean time use of 29.6 hours per month (range 8-100). Deaf individuals matching in age and gender served as controls.
Mobile phone use was identified by a questionnaire.



Exposure Parameters
Exposure 1:
Exposure duration: mobile phone use of a mean time of 29.6 hours/month during 12.5 years

Exposure 1

Main characteristics
Exposure duration mobile phone use of a mean time of 29.6 hours/month during 12.5 years
Exposure setup
Exposure source

No parameters are specified for this exposure.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data showed a significant increase in all salivary oxidative stress indices studied in mobile phone users. Salivary flow was increased and total protein, albumin and amylase activity were decreased in mobile phone users.
The authors conclude, that the use of mobile phones may cause oxidative stress and modify the salivary function.
The major limitation to this study is that, under its current design, one cannot exclude the possibility that deafness itself, and not the lack of being exposed to mobile phones, was responsible for the observed reduced oxidative stress in the control group.

Study character:

Study funded by

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