Study type: Medical/biological study (experimental study, observational study)

Effects of acute exposure to the radiofrequency fields of cellular phones on plasma lipid peroxide and antioxidase activities in human erythrocytes. med./bio.

Published in: J Pharm Biomed Anal 2001; 26 (4): 605-608

Aim of study (acc. to author)

To study the effect of acute exposure to radiofrequency fields of cellular phones on some parameters indicative of oxidative stress in healthy male subjects.

Background/further details

Radiofrequency fields of cellular phones may affect biological systems by increasing free radicals, which appear mainly to enhance lipid peroxidation, and by altering the antioxidase activities of human blood thus leading to oxidative stress.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 1, 2 and 4 h
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Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration continuous for 1, 2 and 4 h
Modulation
Modulation type pulsed
Additional info

TDMA

Exposure setup
Exposure source
Setup The cellular phone in standby position was placed in the pocket of the test person with the keypad facing the body.
Parameters

No parameters are specified for this exposure.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • before exposure
  • after exposure

Main outcome of study (acc. to author)

The findings showed that the plasma level of lipid peroxide was significantly increased after 1, 2 and 4 h of exposure to radiofrequency fields of the cellular phone in standby position. Moreover, the activities of superoxide dismutase and total glutathione peroxidase showed significant reduction while the activity of catalase did not decrease significantly.
These data indicate that acute exposure to radiofrequency fields of cellular phones may modulate the oxidative stress of free radicals by enhancing lipid peroxidation and reducing the activation of superoxide dismutase and total glutathione peroxidase, which are free radical scavengers. Therefore, these findings support the interaction of radiofrequency fields of cellular phones with biological systems.

Study character:

Study funded by

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