Medical/biological study (experimental study)

Effects of Exposure to GSM Mobile Phone Base Station Signals on Salivary Cortisol, Alpha-Amylase, and Immunoglobulin A.

Published in: Biomed Environ Sci 2010; 23 (3): 199-207

Aim of study (acc. to author)

To test whether exposure to radiofrequency electromagnetic fields emitted by mobile phone base stations may have effects on salivary alpha-amylase, immunoglobulin A, and cortisol levels in human subjects.
Background/further details: 57 participants (35 females) were randomly allocated to one of three different experimental scenarios (22 participants to scenario 1, 26 to scenario 2, and 9 to scenario 3; for further information see exposure details). In every session saliva samples were taken after 10, 25, and 45 minutes for biochemical analyses.



Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: five times 50 minutes (five sessions)
General information
Test persons were divided into three groups and exposed in three different scenarios of five sessions each: Scenario1: low exposure, high exposure, low exposure, medium exposure, low exposure Scenario2: low exposure, medium exposure, low exposure, high exposure, low exposure Scenario3: low exposure, low exposure, low exposure, low exposure, high exposure
Exposure 1
Main characteristics
Frequency 900 MHz
Exposure duration five times 50 minutes (five sessions)
Exposure setup
Exposure source
Distance between exposed object and exposure source 6 m
Setup antenna mounted on the outer wall of the building; further GSM-900 and GSM-1800 base stations in the area; different exposure levels gained by the use of shielding curtains; wall painted with shielding paint except for the exposure area
Measurand Value Type Method Mass Remarks
power density 5.2 µW/m² - measured - low exposure
power density 153.6 µW/m² - measured - medium exposure
power density 2,126.8 µW/m² - measured - high exposure
Reference articles
Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated material:
Investigated organ system:
Time of investigation:
  • during exposure

Main outcome of study (acc. to author)

In scenario 3 from session 4 to session 5 (from "low" to "high" exposure), a significant increase of cortisol was detected, while in scenarios 1 and 2 (sessions 2-4), a higher concentration of alpha-amylase was observed as compared to that in scenario 3. Immunoglobulin A concentration was not significantly related to the exposure.
The authors conclude that radiofrequency electromagnetic fields in considerably lower power flux densities than ICNIRP-guidelines may influence certain psychobiological stress markers.
Study character:

Study funded by

  • Land Salzburg Federal Government, Austria
  • Mr. Daniell Porsche, Chairman of the Paracelsus-School at St. Jakob am Thurn, Salzburg, Austria

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