Study type: Medical/biological study (experimental study)

Effect of whole-body exposure to the 848.5 MHz code division multiple access (CDMA) electromagnetic field on adult neurogenesis in the young, healthy rat brain. med./bio.

Published in: Int J Radiat Biol 2015; 91 (4): 354-359

Aim of study (acc. to author)

The effects of an acute whole body exposure of rats to a 848.5 MHz electromagnetic field on the neurogenesis in the adult brain should be investigated.

Background/further details

36 rats were into the 6 following groups (n=6 per group): 1) cage control for 1 h and 2) 8 h exposure per day, 3) sham exposure for 1h and 4) 8 h exposure per day , 5) exposure for 1 h and (6) 8 h per day. All experiments were repeated three times.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 845.5 MHz
Exposure duration: continuous for 1 h daily, 5 days per week, for 2 weeks
Exposure 2: 845.5 MHz
Exposure duration: continuous for 8 h daily, 5 days per week, for 2 weeks

Exposure 1

Main characteristics
Frequency 845.5 MHz
Type
Exposure duration continuous for 1 h daily, 5 days per week, for 2 weeks
Exposure setup
Exposure source
Chamber size of each cage was 39 Π23.5 Π18 cm
Setup a realistic CDMA signal was generated inside the reverberation chamber (240 Œ 232.5 Œ 161.6 cm, wall thickness 12.5 cm); there was a wooden table (140 Œ 100 x 70 cm ) inside the chamber, on which a maximum of eight animal cages could be placed with no change in field uniformity; electromagnetic waves in the experimental region of the reverberation chamber came from all directions, with equal amplitude; room temperature was controlled at 22 ± 2°C
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 2 W/kg mean measured and calculated whole body -
power 8.13 W - - - -

Exposure 2

Main characteristics
Frequency 845.5 MHz
Type
Exposure duration continuous for 8 h daily, 5 days per week, for 2 weeks
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 2 W/kg mean measured and calculated whole body -
power 8.13 W - - - -

Reference articles

  • Kim HS et al. (2013): Effects of Whole-Body Exposure to 915 MHz RFID on Secretory Functions of the Thyroid System in Rats.
  • Kim HS et al. (2013): The effects of exposure to 915 MHz radiofrequency identification on cerebral glucose metabolism in rat: a [F-18] FDG micro-PET study.
  • Lee HJ et al. (2010): The lack of histological changes of CDMA cellular phone-based radio frequency on rat testis.
  • Jung KB et al. (2008): Development and validation of reverberation-chamber type whole-body exposure system for mobile-phone frequency.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No significant differences in cell proliferation were found between the exposure groups (5 and 6) and the corresponding sham exposure groups (3 and 4) and cage control groups (1 and 2) in the investigated brain areas.
The authors conclude that they could not find any effect of an acute whole body exposure of rats to a 848.5 MHz electromagnetic field on the neurogenesis in the adult brain.

Study character:

Study funded by

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