Study type: Medical/biological study (experimental study)

The Effects of 900 Megahertz Electromagnetic Field Applied in the Prenatal Period on Spinal Cord Morphology and Motor Behavior in Female Rat Pups. med./bio.

Published in: Neuroquantology 2013; 11 (4): 573-581

Aim of study (acc. to author)

The effects of prenatal exposure of female rats to a 900 MHz electromagnetic field on spinal cord morphology and motor activity in young rats should be investigated.

Background/further details

Pregnant rats were either exposed or not exposed (n=3, respectively). When rat pups were 21 days old, female pups from non-exposed mothers were assigned to the control group (n=13) and pups from exposed mothers were assigned to the exposure group (n=10). At the age of 26 days, motor activity tests were conducted and at the age of 32 days, rats were killed and histological examinations were conducted.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: intermittent for 1 hour/day from day 13 to 21 of pregnancy

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration intermittent for 1 hour/day from day 13 to 21 of pregnancy
Exposure setup
Exposure source
Chamber plexiglass jar of 30 cm x 42 cm x 52 cm
Setup half-wave dipole antenna made from a copper rod (1 mm x 15 cm) was inserted into the central area of the jar, approximately 11 cm inside the open surface of the jar
Additional info exposure and control groups were maintained in separate cages in the same room during the experiment, except during exposure to EMF, which took place in the EMF exposure room
Parameters
Measurand Value Type Method Mass Remarks
power 300 mW - - - approximate output power
electric field strength 10 V/m mean calculated - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Motor coordination and balance were significantly increased in exposed rats compared to the control group, while motor activity did not show any significant differences between the groups.
No pathologic changes were found in spinal cord samples from control rats, while exposed rats showed atrophy, vacuolization in gray matter and occasional myelin thickening, white matter infiltration among the nerve fibers and infiltration of gray matter inside white matter as well as structural impairment in motor neuron cell body structure.
The authors conclude that prenatal exposure of female rats to a 900 MHz electromagnetic field might affect spinal cord morphology which might cause a change in motor functions in young rats.

Study character:

Study funded by

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