Rats were divided into 4 groups (n= 10 per group): 1.) control group treated with 0.9 % saline, 2.) treated with melatonin (2 mg/kg per day), 3.) exposed and 4.) exposed + melatonin (2 mg/kg per day).
Modulation type: CW
Exposure duration: continuous for 4 h/day on 60 days
|electric field strength||9.88 V/m||minimum||measured||-||-|
|electric field strength||18.35 V/m||maximum||measured||-||-|
|magnetic flux density||4.68 µT||minimum||measured||-||-|
|magnetic flux density||8.69 µT||maximum||measured||-||-|
|SAR||0.043 W/kg||minimum||calculated||whole body||-|
|SAR||0.135 W/kg||maximum||calculated||whole body||-|
Significant body mass reduction was noted in exposed animals when compared to the control group after 20, 40 and 60 days. An administration of melatonin (group 2) caused a significant increase in body weight after 20 days in comparison to the control group. Exposed rats, treated with melatonin, showed a significant increase in body mass after 20 days when compared to the exposed rats.
After 10 days of exposure, changes in the behavior of the rats occurred, which became more intensive with a maximum after 60 days: In both exposure groups, a reduced locomotor activity was noticed in comparison to the unexposed groups, but no differences between the exposure group with melatonin administration and the exposure group without melatonin administration occurred. The exposed animals, not treated with melatonin, showed more anxiety and agitation (more grooming, moving away from the source of exposure) and less exploratory behavior (less rearing) than the unexposed groups. The exposed animals treated with melatonin, showed less stress compared to the exposed rats without melatonin administration.
The authors conclude that microwave exposure could cause a body mass decrease and anxiety related behavior. However, treatment with melatonin could cause a reverse of those effects.