運営予算上の理由により、無線周波電磁界に関する新規文献情報の掲載を2017年11月27日より中断しております。大変ご不便をお掛けして申し訳ありません。適宜最新の状況をお知らせ致しますので、引き続きよろしくお願い致します。なお、電磁界情報センター(JEIC)の電磁界情報データベース(http://www.jeic-emf.jp/database.html)では、引き続き関連情報の検索が可能ですので、そちらをご活用下さい。
ホーム
医学/生物学の研究 (experimental study)

[雌の仔ラットの脊髄の形態および運動行動に対する出生前の900メガヘルツ電磁界へのばく露の影響]

The Effects of 900 Megahertz Electromagnetic Field Applied in the Prenatal Period on Spinal Cord Morphology and Motor Behavior in Female Rat Pups.

掲載誌: Neuroquantology 2013; 11 (4): 573-581

The detailed summary of this article is not available in your language or incomplete. Would you like to see a complete translation of the summary? Then please contact us →

研究目的(著者による)

The effects of prenatal exposure of female rats to a 900 MHz electromagnetic field on spinal cord morphology and motor activity in young rats should be investigated.
詳細情報: Pregnant rats were either exposed or not exposed (n=3, respectively). When rat pups were 21 days old, female pups from non-exposed mothers were assigned to the control group (n=13) and pups from exposed mothers were assigned to the exposure group (n=10). At the age of 26 days, motor activity tests were conducted and at the age of 32 days, rats were killed and histological examinations were conducted.

影響評価項目

  • 神経系への影響: spinal cord morphology and motor activity in young rats

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
ばく露時間: intermittent for 1 hour/day from day 13 to 21 of pregnancy
ばく露1
主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 intermittent for 1 hour/day from day 13 to 21 of pregnancy
ばく露装置
ばく露の発生源/構造
チャンバの詳細 plexiglass jar of 30 cm x 42 cm x 52 cm
ばく露装置の詳細 half-wave dipole antenna made from a copper rod (1 mm x 15 cm) was inserted into the central area of the jar, approximately 11 cm inside the open surface of the jar
Additional information exposure and control groups were maintained in separate cages in the same room during the experiment, except during exposure to EMF, which took place in the EMF exposure room
パラメータ
測定量 種別 Method Mass 備考
電力 300 mW - - - approximate output power
電界強度 10 V/m mean 計算値 - -
Additional parameter details
electrical field strength was equivalent to the intensity of the electrical field emitted by mobile phones in speak mode in their immediate surroundings
ばく露を受けた生物:
  • 動物
  • rat/Sprague-Dawley
  • 全身

方法 影響評価項目/測定パラメータ/方法

  • 形態学/組織学的変化: spinal cord histology of upper thoracic region (cresyl violet stain, microscopy)
  • 認知的/行動学的影響評価項目: motor activity (number of squares crossed and numbers of rearings (inquisitive investigation of surroundings by rising onto its hind legs), anxiety (number of defecations); open field test), motor coordination and balance (time until fall down; accelerating rotating rod test)
研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

Motor coordination and balance were significantly increased in exposed rats compared to the control group, while motor activity did not show any significant differences between the groups.
No pathologic changes were found in spinal cord samples from control rats, while exposed rats showed atrophy, vacuolization in gray matter and occasional myelin thickening, white matter infiltration among the nerve fibers and infiltration of gray matter inside white matter as well as structural impairment in motor neuron cell body structure.
The authors conclude that prenatal exposure of female rats to a 900 MHz electromagnetic field might affect spinal cord morphology which might cause a change in motor functions in young rats.
研究の種別:
  • 医学/生物学の研究
  • experimental study
  • full/main study

研究助成

  • 記載なし/研究助成なし

関連論文

  • Odaci E et al. (2016): [900MHz連続波電磁界への母体ばく露はその仔である32日齢雌ラットの小脳に神経細胞損失および病理学的変化を起こす]
  • Erdem Koc G et al. (2016): [900MHz電磁界に出生前ばく露した海馬細胞におけるメラトニンおよびオメガ3の神経保護作用]
  • Klose M et al. (2014): [幼若齢期に開始した無線周波電磁界ばく露(GSM900MHz)がラットの行動および記憶に与える影響]
  • Haghani M et al. (2013): [母親の携帯電話ばく露は仔ラットのプルキンエニューロンの電気生理学的特性に有害に作用する]
  • Ikinci A et al. (2013): [仔ラットの海馬の形態および学習行動に対する900メガヘルツ電磁界への出生前ばく露の影響]
  • Bas O et al. (2013): [出生前の妊娠13日から21日まで900メガヘルツ電磁界にばく露した32日齢の雌ラットのアンモン角の錐体細胞消失]
  • Khirazova EE et al. (2012): [ラットにおける幾つかの生理学的及び生化学的パラメータに対するGSM周波数電磁界放射の影響]
  • Sokolovic D et al. (2012): [携帯電話からのマイクロ波放射へのばく露中のラットの体質量及び行動に対するメラトニンの影響]
  • Divan HA et al. (2012): [幼児の携帯電話使用と行動学的問題]
  • Ragbetli MC et al. (2009): [マウス海馬の錐体細胞数に対する携帯電話への出生前ばく露の影響:立体学的研究]
  • Bas O et al. (2009): [900 MHz電磁界への出生前の慢性ばく露は新生仔ラットの海馬の錐体細胞消失を生じる]
  • Divan HA et al. (2008): [携帯電話使用への出生前及び出生後のばく露と子どもの行動学的問題]
  • Odaci E et al. (2008): [ラット歯状回に対する900 MHz電磁界の出生前ばく露の影響:立体学的および組織病理学的研究]
  • Kumlin T et al. (2007): [携帯電話からの放射と発達中の脳:幼若ラットにおける行動的および形態学的影響]
  • Dubreuil D et al. (2003): [GSM900 MHz電磁界への頭部ばく露はラットの空間認知を変えない]
  • Dubreuil D et al. (2002): [ラットの空間学習タスクにGSM-900電磁界の頭部ばく露は影響するか?]