Pregnant dams were divided in an exposure and sham exposure group (n=5 respectively). The exposed dams gave birth to 37 pups and the sham exposed to 63 pups. Pups were killed after 28 or 43 days for brain examinations.
Exposure duration: 2 hours/day during gestation
No parameters are specified for this exposure.
Rooting reflex was significantly reduced but consisted longer in prenatal exposed rat pups when compared to sham exposed pups. Additionally, the development of the righting reflex and the negative geotaxis reflex were significantly delayed in exposed pups compared to sham exposed pups. The rotarod performance test and the suspension test showed that motor ability was significantly worse in exposed pups compared to sham exposed ones. Exposed pups opened their eyes one day earlier then sham exposed ones.
Oxidative stress parameters were significantly different in rats killed and examined after 28 days: The lipid peroxidation and level of hydrogen peroxide were significantly increased in exposed rats compared to sham exposed ones while the enzyme activities of superoxide dismutase and catalase were significantly decreased. However, in 43 day old exposed rats, only the level of hydrogen peroxide was increased when compared to 43 day old sham exposed rats.
The enzyme activity of acetylcholinesterase was significantly increased in 28 and 43 day old exposed rats when compared to sham exposed rats of the same age while the enzyme activity of butrylcholinesterase was significantly decreased in 43 day old exposed rats.
The authors conclude that prenatal exposure of rats to a WiFi signal could impair neurodevelopment of rat pups and induce biochemical alterations in the brain of young rats but has no behavioral effects.