To study the effect of weak 8.15-18 GHz microwaves on the tumor necrosis factor secretion and immune response. The aim of the study was to elucidate whether there is a synergism of the immunostimulating effects of low-intensity microwaves and antioxidants (beta-carotene, alpha-tocopherol, and ubiquinone Q9 were given daily with food prior to microwave exposure).
Exposure duration: continuous for 5 h
All details on irradiation described in the reference article
|Exposure duration||continuous for 5 h|
|Additional info||Animals (n=100) were divided in the following manner: n=40 control-cage mice, n=40 antioxidants-fed mice, n=20 sham exposed mice. Half of control-cage and antioxidants-fed groups were exposed to microwave irradiation.|
|Sham exposure||A sham exposure was conducted.|
|power density||1 µW/cm²||-||-||-||-|
A single 5 h exposure induced a significant increase in tumor necrosis factor production in peritoneal macrophages and splenic T cells. The mitogenic response in T lymphocytes increased after microwave exposure. The activation of cellular immunity was revealed within 3 days after irradiation. The diet containing antioxidant nutrients increased the activity of macrophages and T cells from exposed animals.
These data demonstrate that irradiation with low-power density microwaves stimulates the immune potential of macrophages and T cells. The antioxidant treatment enhances the effect of microwaves, in particular at later terms, when the effect of irradiation is reduced.