Study type: Medical/biological study (experimental study)

Microwaves and cellular immunity. II. Immunostimulating effects of microwaves and naturally occurring antioxidant nutrients. med./bio.

Published in: Bioelectrochem Bioenerg 1999; 49 (1): 37-41

Aim of study (acc. to author)

To study the effect of weak 8.15-18 GHz microwaves on the tumor necrosis factor secretion and immune response. The aim of the study was to elucidate whether there is a synergism of the immunostimulating effects of low-intensity microwaves and antioxidants (beta-carotene, alpha-tocopherol, and ubiquinone Q9 were given daily with food prior to microwave exposure).



Exposure Parameters
Exposure 1: 8.15–18 GHz
Exposure duration: continuous for 5 h

General information

All details on irradiation described in the reference article

Exposure 1

Main characteristics
Frequency 8.15–18 GHz
Exposure duration continuous for 5 h
Additional info Animals (n=100) were divided in the following manner: n=40 control-cage mice, n=40 antioxidants-fed mice, n=20 sham exposed mice. Half of control-cage and antioxidants-fed groups were exposed to microwave irradiation.
Exposure setup
Exposure source
  • not specified
Sham exposure A sham exposure was conducted.
Measurand Value Type Method Mass Remarks
power density 1 µW/cm² - - - -

Reference articles

  • Fesenko EE et al. (1999): Microwaves and cellular immunity. I. Effect of whole body microwave irradiation on tumor necrosis factor production in mouse cells.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

A single 5 h exposure induced a significant increase in tumor necrosis factor production in peritoneal macrophages and splenic T cells. The mitogenic response in T lymphocytes increased after microwave exposure. The activation of cellular immunity was revealed within 3 days after irradiation. The diet containing antioxidant nutrients increased the activity of macrophages and T cells from exposed animals.
These data demonstrate that irradiation with low-power density microwaves stimulates the immune potential of macrophages and T cells. The antioxidant treatment enhances the effect of microwaves, in particular at later terms, when the effect of irradiation is reduced.

Study character:

Study funded by

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