Study type: Medical/biological study (experimental study)

Single millimeter wave treatment does not impair gastrointestinal transit in mice. med./bio.

Published in: Life Sci 2002; 71 (15): 1763-1770

Aim of study (acc. to author)

To study whether a single millimeter wave treatment, that can produce opioid-related hypoalgesia, may also retard gut transit and colorectal passage in mice.

Background/further details

Endogenous and exogenous opioids are known to suppress gastrointestinal transit; the authors hypothesize that endogenous opioids are involved in millimeter wave treatment-induced hypoalgesia.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 61.22 GHz
Exposure duration: 15 min

Exposure 1

Main characteristics
Frequency 61.22 GHz
Type
Waveform
Exposure duration 15 min
Exposure setup
Exposure source
Setup mice restrained in a plastic tube (8 cm long and 2.6 cm inner diameter).
Additional info mouse nose was uncovered for exposure purpose
Parameters
Measurand Value Type Method Mass Remarks
power density 15 µW/cm² unspecified measured unspecified -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data have shown that millimeter wave treatment does not significantly change small intestinal or colonic transit in mice. Thus, suppression of gastrointestinal motility should not be a setback in the clinical use of millimeter wave treatment.

Study character:

Study funded by

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