Two hypothesis were tested: a) that radiofrequency radiation (RFR) by itself can cause an increase in mutation in a mammalian cell in vitro mutation assay system; and b) that a simultaneous exposure to RFR during a chemical treatment of the cells with the genotoxic chemical mitomycin C will result in either an increase or a decrease in the extent of mutagenesis induced by the treatment of the cells by the chemical alone.
|Pulse width||10 µs|
|Duty cycle||0.25 %|
|Repetition frequency||25,000 Hz|
Radiofrequency radiation alone, at moderate power levels which resulted in a temperature increase in the cell culture medium less than 3°C, is not mutagenic. When cells are simultaneously treated with mitomycin C and radiofrequency radiation (RFR) at these same moderate power levels, the RFR does not affect either the inhibition of cell growth or the extent of mutagenesis resulting from treatment with mitomycin C alone.