EMF-Portal | Effect of amplitude modulated RF radiation on calcium ion efflux and ODC activity in chronically exposed rat brain

Effect of amplitude modulated RF radiation on calcium ion efflux and ODC activity in chronically exposed rat brain med./bio.

By: Paulraj R, Behari J, Rao AR

Published in: Indian J Biochem Biophys 1999; 36 (5): 337-340

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Aim of study (acc. to editor)

Endpoint

Exposure

Exposure	Parameters
Exposure 1: 112 MHz Modulation type: AM Exposure duration: 2 h/day for 35 days	power density: 1 mW/cm² SAR: 0.75 W/kg

Exposure 1

Main characteristics

Frequency	112 MHz
Type	electromagnetic field
Exposure duration	2 h/day for 35 days

Modulation

Modulation type	AM
Modulation frequency	16 Hz

Exposure setup

Exposure source	TEM cell
Chamber	Plexiglas cages 32 cm x 10 cm x 9 cm
Sham exposure	A sham exposure was conducted.
Additional info	long axis parallel to the electric component.

Parameters

Measurand	Value	Type	Method	Mass	Remarks
power density	1 mW/cm²	-	-	-	-
SAR	0.75 W/kg	-	-	-	-

Exposed system:

animal
rat/Wistar
whole body

Methods Endpoint/measurement parameters/methodology

Investigated system:

isolated bio./chem. substance

Investigated organ system:

brain/CNS

Time of investigation:

after exposure

Main outcome of study (acc. to author)

Exposed rats showed a significant increase in the activity of ODC and an enhanced calcium efflux.

Study character:

medical/biological study
experimental study
full/main study

Study funded by

not stated/no funding

Maskey D et al. (2013): Neuroprotective effect of ginseng against alteration of calcium binding proteins immunoreactivity in the mice hippocampus after radiofrequency exposure

Kesari KK et al. (2012): Pathophysiology of microwave radiation: effect on rat brain

Maskey D et al. (2010): Effect of 835 MHz radiofrequency radiation exposure on calcium binding proteins in the hippocampus of the mouse brain

Maskey D et al. (2010): Chronic 835-MHz radiofrequency exposure to mice hippocampus alters the distribution of calbindin and GFAP immunoreactivity

Platano D et al. (2007): Acute exposure to low-level CW and GSM-modulated 900 MHz radiofrequency does not affect Ba(2+) currents through voltage-gated calcium channels in rat cortical neurons

Dutta SK et al. (1984): Microwave radiation-induced calcium ion efflux from human neuroblastoma cells in culture