Study type: Medical/biological study (experimental study)

Influence of exposure to electromagnetic field on the cardiovascular system. med./bio.

Published in: Auton Autacoid Pharmacol 2005; 25 (1): 17-23

Aim of study (acc. to author)

To study whether extremely low frequency electromagnetic fields affect the basal level of cardiovascular parameters and influence of drugs acting on the sympathetic nervous system.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 60 Hz
Exposure duration: continuous for 1 day
Exposure 2: 60 Hz
Exposure duration: continuous for 5 day

Exposure 1

Main characteristics
Frequency 60 Hz
Type
Waveform
  • unspecified
Exposure duration continuous for 1 day
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2 mT unspecified unspecified - -

Exposure 2

Main characteristics
Frequency 60 Hz
Type
Waveform
  • unspecified
Exposure duration continuous for 5 day
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2 mT unspecified unspecified - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In terms of the basal levels, there were no statistically significant differences among control and electromagnetic field exposure in PR interval, QRS complex interval, mean blood pressure, heart rate and pulse pressure. However, the QT interval, representing ventricular repolarization, was significantly reduced by the one day electromagnetic field exposure.
(-)-Dobutamine (beta1-adrenoceptor-selective agonist)-induced tachycardia was significantly suppressed by extremely low frequency electromagnetic field exposure in the one day exposure group. Adrenaline (nonselective beta-receptor agonist)-induced dysrhythmia was also significantly suppressed by extremely low frequency electromagnetic fields in the one day exposure group.
These data indicated that one day exposure to extremely low frequency electromagnetic fields could suppress the increase in heart rate by affecting ventricular repolarization and may have a down-regulatory effect on responses of the cardiovascular system induced by sympathetic agonists.

Study character:

Study funded by

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