Study type: Medical/biological study (experimental study)

Low dose magnetic fields do not cause oxidative DNA damage in human placental cotyledons in vitro. med./bio.

Published in: Virchows Arch 2005; 446 (6): 634-639

Aim of study (acc. to author)

This in vitro study was performed in order to gain an insight into potential effects of low intensity magnetic fields in human placental tissue.

Background/further details

8-hydroxy-2-deoxyguanosine was taken as marker of oxidative DNA damage.
31 placentas were used.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 3 h

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration continuous for 3 h
Exposure setup
Exposure source
Setup electromagnet constructed by wounding a copper wire on a ferromagnetic core of 20 mm diameter; the magnetic field was uniformly distributed over the surface of 17.6 cm², ensuring exposure to the whole cotyledons
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2 mT unspecified measured - -
magnetic flux density 5 mT unspecified measured - -

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No statistical significant differences in the 8-hydroxy-2-deoxyguanosine contents were observed.

Study character:

Study funded by

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