Study type: Medical/biological study (experimental study)

Acute exposure to a 60 Hz magnetic field increases DNA strand breaks in rat brain cells. med./bio.

Published in: Bioelectromagnetics 1997; 18 (2): 156-165

Aim of study (acc. to author)

To study the effects of acute exposure to a 60 Hz magnetic field on DNA damage in brain cells of the rat.

Background/further details

DNA strand breaks have been correlated with carcinogenicity, cell death, aging, and neurodegenerative diseases.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 60 Hz
Exposure duration: 2 h

Exposure 1

Main characteristics
Frequency 60 Hz
Type
Waveform
Exposure duration 2 h
Exposure setup
Exposure source
Chamber plastic cage (45 cm long x 21 cm wide x 22 cm high)
Setup cages placed in the center of the space between the coils
Parameters
Measurand Value Type Method Mass Remarks
power 8 W maximum - - -
magnetic flux density 100 µT minimum - unspecified -
magnetic flux density 0.25 mT - - - -
magnetic flux density 0.5 mT maximum - - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Acute (2 h) exposure of rats to a 60 Hz magnetic field caused a dose-dependent increase in DNA strand breaks in brain cells of the animals (4 h post-exposure). An increase in DNA single-strand breaks was found after exposure to magnetic fields of 0.1, 0.25, and 0.5 mT, whereas an increase in DNA double-strand breaks was revealed at 0.25 and 0.5 mT.

Study character:

Study funded by

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