Study type: Epidemiological study (observational study)

Mobile phone use and risk of parotid gland tumor epidem.

Published in: Am J Epidemiol 2006; 164 (7): 637-643

Aim of study (acc. to author)

A population-based case-control study was conducted in Denmark and Sweden to test the hypothesis that long-term use of mobile phones increases the risk of parotid gland tumors.

Further details

Regular use of mobile phone was defined as use of a mobile phone on average once per week during 6 months or more one year prior diagnosis.
The study is based on the Danish and Swedish parts of the INTERPHONE project (publications 11887, 10496, 11648, and 9105).

Endpoint/type of risk estimation

Type of risk estimation: (odds ratio (OR))



Exposure groups

Group Description
Reference group 1 never or nonregular use
Group 2 regular use
Group 3 duration of use < 5 years
Group 4 duration of use 5-9 years
Group 5 duration of use ≥ 10 years
Group 6 time since first regular use < 5 years
Group 7 time since first regular use 5-9 years
Group 8 time since first regular use ≥ 10 years
Group 9 cumulative use < 30 hours
Group 10 cumulative use 30-449 hours
Group 11 cumulative use ≥ 450 hours
Group 12 cumulative number of calls ≤ 624
Group 13 cumulative number of calls 625-7349
Group 14 cumulative number of calls ≥ 7350
Reference group 15 ipsilateral exposure: no use or contralateral use
Group 16 ipsilateral exposure: regular use
Reference group 17 contralateral exposure: no use or ipsilateral use
Group 18 contralateral exposure: regular use


Case group

Control group

Study size

Cases Controls
Eligible 199 966
Participants 172 681
Participation rate 85 % 70 %

60 cases of malignant parotid gland tumors, 112 cases of benign pleomorphic adenomas

Statistical analysis method: (adjustment: )

Results (acc. to author)

No increased risk for regular mobile phone use and parotid gland tumors was observed, regardless of duration. The risk estimate did not increase with the amount of use nor for use mainly in rural or urban areas. Analyses of digital and analog mobile phone use separately did not show any increased risks.
The results do not support the hypothesis that exposure to electromagnetic fields generated by mobile phones increase the risk of malignant or benign parotid gland tumors.

Study funded by

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